Wednesday, November 27, 2019

Versions of Romeo and Juliet Essay Example For Students

Versions of Romeo and Juliet Essay The version which sticks closer to the play is Zefferellis version. Its more like what the scenery was like when it was written and would of take place then. The one that was more successful in my opinion is the Lurmans version, its more modern and more enjoyable to watch. I prefer Lurhmans simply because it is basically modern. I dont think I would be able to watch and enjoy Zefferellis because of the scenery and how old it is. Lurhmans is better to enjoy and would rather by me because new is better. Zefferellis can offer the background clothes and language used in his version. Lurhmans it again modern in his version. In his version they use props and clothes that we use today. The buildings in Zefferellis are palaces and castles and are replaced by buildings and office blocks. We will write a custom essay on Versions of Romeo and Juliet specifically for you for only $16.38 $13.9/page Order now The costumes and props used in Zefferellies film the period i.e swords and daggers and period clothing. Lurhmans they replaced swords with guns as well as replacing horses with cars. Costumes where what we wear today. The music in each version are what you would hear in that time. Zefferellis version, the music that was played was by a single hand trumpet and the type of tune played was dictated by the scene on screen i.e slow for conversations and fierce for fight scenes. Lurhmans soundtrack was orchestral instruments of operatic voices through other types of music i.e dance music, rock music for party scenes and background radio of a modern type was used. The scenery and settings of the play were changed, the palaces and mansions of old Verona were replaced with modern buildings and office blocks. They are very different from each other. Zefferellis had little fruit stalls and someone behind selling the fruit. In Lurhmans version is basically replaced with shops selling a lot more than fruit. The interpretation of characters is (to me) very different from each other. I think Id get through Lurhmans movie understanding whats being said more than Zefferellis movie. The language in Lurhmans is more understanding than Zefferellis definitely. The way they dress is different, tights to trousers and so on. Rucushio in the modern one is more lively and understandable. In the old one he doesnt really know what hes on about, hes a step in step out person. The themes of the plays that I see if love, hatred, revenge, life and death. Maybe not a lot of revenge in Zefferellis. Lurhmans has everything, you can feel the themes of his version when watching his movie. Zefferellis you just cant really enjoy it mostly because its old. The concepts I would use if I was to stage William Shakespeares Romeo and Juliet would be the modern language, the modern setting and clothes. Maybe the guns instead of the swords, or using the guns and the swords in the one play. Make the setting what its like today not 6-7 years ago even though nothing has changed a bit. A scene I want to compare in both versions of Romeo and Juliet is the scene just at the end of each film at the chapel. They have different arrangements that happen through the whole scene. Zefferellis takes place in a dark, quiet room that isnt all that big. Romeo takes poison says his last goodbyes then Juliet awakes then is devastated and stabs herself with a dagger. Lurhmans version, Romeo takes poison, Juliet wakes up and shoots herself with a gun and they are in a much bigger chapel with neons and candles all around. My conclusion of what I have proved is that a lot has changed, the background, then clothes and the movie. We are in their 2000s not the 1900s or 1800s any more.

Sunday, November 24, 2019

Pharmaceutical products Essay Example

Preposterous costs of Biotech/ Pharmaceutical products Essay Example Preposterous costs of Biotech/ Pharmaceutical products Paper Preposterous costs of Biotech/ Pharmaceutical products Paper Biotech / Pharmaceutical companies incur huge costs in brining a drug to the market. This paper details the process of drug development right from the stage of preclinical trials to the final stage when the drug gets FDA approval. The paper gives an insight about the costs incurred by the companies in the drug development process. Considering the specific example of Genentechs controversial anti-cancer drug Avastin, its cost is compared with the value it delivers to its customer (a person suffering from cancer). Drug development is a very costly affair which involves high risks. Though the risks in the process of drug development overweigh the benefits, the drug manufacturers are motivated to undertake such a process because of the current patent laws which promise a good reward for a comparatively good product. Moreover, the very survival of many of the pharmaceutical companies world over depend to a large extent on the new products coming out of their pipeline. Thus pharmaceutical companies world over invest billions of dollars every year in the development of new drugs. No doubt they try to get back the money that they invest from their customers. The success rate of developing a new drug is shockingly low. Not every drug tested in the laboratory is launched in the market. A drug has to undergo several stages of development before it is successfully launched in the market. A company has to screen through many thousand compounds that show promising result before it could take on the task of development of a promising compound. This eventually increases the cost of development of drug as many compounds that are tested are discarded in the preliminary stages of development. For every 1,000 compounds that are identified by a company, only about 30 show promising results. And for every 30 compounds that show promise, three get past the first round of clinical trials and finally, only one hit the market. Sometimes compounds are to be dropped off during regulatory approval process. Thus, to introduce one new drug, a company needs to start with many thousands of compounds. (Janodia, Manthan 2007) The process of drug development is a very slow one and it is scrutinized at every stage by the FDA. According to PhRMA (Pharmaceutical Research and Manufacturers of America), on an average it takes around 12 to 15 years to develop a new drug. This crawling rate of drug development can be attributed to the numerous stages that are involved in the process of drug development. Even before the drug is tested on humans, it needs to undergo the process of preclinical testing where it is tested on animals. The different phases of preclinical testing preceded by drug discovery consume around 6.5 years. The three phases of clinical trials (before the market launch and FDA approval) require around 7 years. It would take around one and a half years to assess the safety of the drug on healthy volunteers in phase I trials. The effectiveness of the drug needs to be proved in the phase II trials which consumes around 2 years. To confirm the pharmacological actions of the drug and also its effects on long term use need to be studied on a few thousands of humans which requires around three and a half years. Further, one and a half years of post marketing clinical data analysis needs to be done before the FDA approval for the drug could be obtained successfully. Let us now have a look at the different stages of the drug development process.

Thursday, November 21, 2019

Assignment Example | Topics and Well Written Essays - 750 words - 18

Assignment Example Methodology- to compare between effectiveness of problem-focused or emotion-focused coping strategies, authors analyzed the situation using coded semi-structured interviews from 116 German expatriates when each half were on their assignments in Japan and the USA. The responses were then exposed to moderated regression analysis technique to arrive at conclusions. Findings- the authors presented 966 problem events to the interviewees and out of 3913 coping actions they ranked 30 coping strategies by frequency of use. Results revealed that majority of the strategies were problem-focused like resignation, comparisons, change seeking, ethnocentricism, et cetera. Others were emotion-focused. Implications- the findings revealed that managers at lower levels of hierarchy used problem-focused strategies more often since they need to adjust more to the situations. Moreover, it was also observed that expatriates in culturally more distant countries benefitted more from problem-focused strategies. However, these strategies did not encourage the expatriates to continue with their international assignments. Rather culturally similar nation and longer duration of international assignments encouraged the expatriates to continue. This signifies that cross-cultural dimensions are antecedent to expatriate intentions behind international assignment continuation. Value to readers- expatriation has been researched mostly with the perspective of multinational corporations and countries on whole. This piece of study is majorly devoted to the actual expatriates and their dilemma of coping with the new and unadjusted environment. Some strategies are available to some expatriates while others to other expatriates. Expatriates having social support and friend circle are found to be more adjusted and have more coping strategies with them. Thus, this study provides an insight into how coping